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Resistance to emtricitabine is more common, likely because only a single resistance mutation is required to confer resistance to that drug, while for tenofovir more than one mutation is usually required. To read the conference abstract, click hereand to view the conference presenation webcast, click here. Please confirm that you are a Human by entering security code from the image below. As a free member you getting:. Such username already exists in the database. A message with confirmation link was sent to your email address.

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The man in the case study reported multiple acts of receptive anal intercourse without a condoms during the two-to-six week period before testing postivie for HIV.

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It had numerous nucleoside reverse transcriptase inhibitor NRTI resistance mutations, including those known as 41L, 67G, 69D, 70R, V and E, which in the resistance tests reduced the response to Ziagen abacavir by 1. Tests also indicated that his drug resistance had been transmitted from another person, rather than acquired post-transmission, and that he had contracted the virus from a single person. Click here to log back in. The scientists concluded that it is indeed possible for individuals who are adherent to PrEP to contract HIV when they are exposed to a virus that is resistant to both drugs included in Truvada. Please confirm your registration to activate your account.

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Please confirm your registration to activate your account. A message with confirmation link was sent to your email address. This figure comes from the iPrEX open-label extension study, which used mathematical modeling to reach this estimate. These cases apparently stress the importance of using two drugs for PrEP rather than one, even in the absence of resistant virus—at least when using the components of Truvada. Such username already exists in the database.

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